Course syllabus for Drug development

Course syllabus adopted 2020-02-19 by Head of Programme (or corresponding).

Overview

  • Swedish nameUtveckling av läkemedel
  • CodeKMG046
  • Credits7.5 Credits
  • OwnerMPBIO
  • Education cycleSecond-cycle
  • Main field of studyBioengineering
  • DepartmentKEMI OCH MOLEKYLÄRBIOLOGI (GU)
  • GradingTH - Pass with distinction (5), Pass with credit (4), Pass (3), Fail

Course round 1

  • Teaching language English
  • Application code 08135
  • Maximum participants40
  • Open for exchange studentsYes

Credit distribution

0114 Examination 7.5 c
Grading: TH		 7.5 c
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Examiner

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Eligibility

General entry requirements for Master's level (second cycle)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Specific entry requirements

English 6 (or by other approved means with the equivalent proficiency level)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Course specific prerequisites

Basic courses in cell and molecular biology.

Aim

The student should be oriented about concepts, working methods and strategies in modern drug development.

Learning outcomes (after completion of the course the student should be able to)

The student should be oriented about:

  • concepts, working methods and strategies in modern drug development, both with respect to small molecules and proteins as drugs.
The student should be able to:
  • Comprehend specific strengths and weaknesses of different genetic model organisms used in target discovery
  • Evaluate the significance of genetic differences between patients in individualised drug therapy
  • Interpret structural information about drug targets in the context of interactions with small molecules
  • Understand fundaments of small molecule screening models
  • Give accounts of the challenges met by drugs that have recently come to the market

Content

This course shall focus on a building an overall understanding of the discovery and development of novel pharmaceuticals (drug discovery/development), covering a wide spectrum of target selection, lead discovery/optimization, nonclinical in vitro/in vivo safety and efficacy studies, clinical trials, and market authorization. Examples are also given of existing drugs, how they have been developed, and their mechanisms of action. The course is mostly theoretical, but in certain parts, practical demonstrations are also included.

Organisation

The course content consists of lectures, seminars, practical demonstrations and written examination.

Literature

Scientific papers selected by the teachers

Examination including compulsory elements

Written, with two components: home essay and final exam.