Course syllabus for Bioanalytical chemistry

Course syllabus adopted 2021-05-20 by Head of Programme (or corresponding).

Overview

  • Swedish nameBioanalytisk kemi
  • CodeBBT055
  • Credits7.5 Credits
  • OwnerMPBIO
  • Education cycleSecond-cycle
  • Main field of studyBioengineering, Chemical Engineering
  • DepartmentBIOLOGY AND BIOLOGICAL ENGINEERING
  • GradingTH - Pass with distinction (5), Pass with credit (4), Pass (3), Fail

Course round 1

  • Teaching language English
  • Application code 08136
  • Maximum participants60 (at least 10% of the seats are reserved for exchange students)
  • Block schedule
  • Open for exchange studentsYes

Credit distribution

0121 Laboratory 3 c
Grading: UG		 3 c
0221 Examination 4.5 c
Grading: TH		 4.5 c

In programmes

Examiner

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Eligibility

General entry requirements for Master's level (second cycle)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Specific entry requirements

English 6 (or by other approved means with the equivalent proficiency level)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Course specific prerequisites

Biochemistry. It is recommended to have studied organic chemistry and physical chemistry

Aim

The course aims at giving knowledge on bioanalytical-chemical nomenclature, methodology, instruments and data analysis with a focus on in industry common applications

Learning outcomes (after completion of the course the student should be able to)

• apply their basic knowledge in biochemistry and analytical chemistry to quickly learn and manage important techniques in bioanalytical chemistry
• describe the analytical process with special regard to life-science-relevant samples
• describe sample preparation and preservation
• describe the various bioanalytical instrumental techniques
• describe analytical applications of biomolecules, such as enzymes and antibodies
• describe the choice of instrumentation techniques for bioanalytical problems
• use the most common instruments in chemical and biochemical analysis and the procedure used to solve problems in analysis.
• generate and evaluate measurement data in analytical experiments
• describe the validation of analytical methods
• understand and evaluate ethical principles and problems within the framework of analytical sciences

Content

• Analytical and bioanalytical nomenclature, concepts of uncertainties, accuracy, precision, sensitivity, detection limit and dynamic range. Validation of analytical methods.
• Overview of analytical problems and analytics in biochemistry, specifically DNA, enzymes and antibodies
• Molecular spectroscopic analysis methods: ultraviolet and visible light (UV-VIS), near infrared (NIR) and fluorescence measurements.
• Analytical separation techniques: gas, liquid and ion chromatography, capillary electrophoresis, supercritical chromatography.
• Applications of mass spectroscopy.
• Immunoassays (quantitative immunoassays)
• Ethical principles in science and technology
• Introduction to project management
• Compulsory laboratory work covers parts of the course content described above with applications in bioanalysis, environmental analysis and quality control.

Organisation

20 lectures, 3 laboratory excersises

Literature

S.R. Mikkelsen & E. Corton: Bioanalytical Chemistry 2nd. ed.
D. Harris: Quantitative Chemical Analysis. 7 eller 8 ed. 

Examination including compulsory elements

Exam and approved laboratory exercises are also required for the final grade.

The course examiner may assess individual students in other ways than what is stated above if there are special reasons for doing so, for example if a student has a decision from Chalmers on educational support due to disability.