Course syllabus for Advanced analytical chemistry: metabolomics and proteomics

The course syllabus contains changes
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Course syllabus adopted 2024-03-14 by Head of Programme (or corresponding).

Overview

  • Swedish nameAvancerad bioanalytisk kemi: metabolomik och proteomik
  • CodeBBT020
  • Credits7.5 Credits
  • OwnerMPBIO
  • Education cycleSecond-cycle
  • Main field of studyBioengineering
  • DepartmentBIOLOGY AND BIOLOGICAL ENGINEERING
  • GradingTH - Pass with distinction (5), Pass with credit (4), Pass (3), Fail

Course round 1

The course round is cancelled. For further questions, please contact the director of studies
  • Teaching language English
  • Application code 08112
  • Maximum participants30 (at least 10% of the seats are reserved for exchange students)
  • Block schedule
  • Open for exchange studentsYes

Credit distribution

0117 Examination 3.5 c
Grading: TH		0 c0 c0 c3.5 c0 c0 c
  • 27 Maj 2024 pm J
  • 06 Okt 2023 pm J
  • 27 Aug 2024 am J
0217 Project 4 c
Grading: TH		0 c0 c0 c4 c0 c0 c

In programmes

Examiner

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Eligibility

General entry requirements for Master's level (second cycle)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Specific entry requirements

English 6 (or by other approved means with the equivalent proficiency level)
Applicants enrolled in a programme at Chalmers where the course is included in the study programme are exempted from fulfilling the requirements above.

Course specific prerequisites

Before enrolment in this course, students should have passed the course BBT055: Bioanalytical chemistry, or passed similar courses, or have equivalent experience.

Aim

The aim of this course is to give an overview of metabolomics and proteomics, and how they can be applied to advance understanding of biology and biological effects.

Learning outcomes (after completion of the course the student should be able to)

  • Design a metabolomics or proteomics experiment to help solve a biological question
  • Critically evaluate the use of different methods for metabolomics and proteomics
  • Critically assess different data analysis tools
  • Understand integration of metabolomics and proteomics data with other types of data

Content

New analytical tools allow us to start embracing the complexity of biological systems and using this to understand how they work and can be manipulated. Among the foremost of these are metabolomics and proteomics methods to measure as many metabolites and proteins as possible. These methods can provide novel insight into how different metabolic reactions are connected and can be altered, and are frequently used in both academic and industrial research environments. Besides basic biological research, both techniques are widely used in food, nutrition and health research.

During this course, you will get a broad overview of what can be done with metabolomics and proteomics, and how this can be applied in practice. You will also get the opportunity to generate your own lab-based data, which will be the basis of practical work on data analysis and the course project.

The course contains the following main topics:
  • Metabolomics using NMR and mass spectrometry
  • Proteomics
  • Advanced applications of proteomics (glycoproteomics, phosphoproteomics)
  • Study design and sample preparation
  • Applications of metabolomics and proteomics in industry
  • Fluxomics
  • Imaging mass spectrometry metabolomics
  • Multivariate data analysis for metabolomics and proteomics
  • Integrating and analysing metabolomics and proteomics data

Organisation

The course includes lectures, study visits, laboratory exercises and a project.

Literature

There is no textbook for this course. Students will be provided with relevant literature and be expected to use available reputable resources on the internet.

Examination including compulsory elements

The course grade will be based on project work, a seminar, laboratory reports and a written exam.

The course examiner may assess individual students in other ways than what is stated above if there are special reasons for doing so, for example if a student has a decision from Chalmers on educational support due to disability.

The course syllabus contains changes

  • Changes to course:
    • 2023-03-15: Prerequisites Prerequisites changed by PA
      Updated prerequisites
  • Changes to course rounds:
    • 2024-03-08: Cancelled Changed to cancelled by UBS/UOL
      [Course round 1] Cancelled
  • Changes to examination:
    • 2024-03-14: Cancelled Changed to cancelled by Lina Haglund
      [2024-05-27 3,5 hec, 0117] Cancelled - cancelled